Drawing from case studies stemming from various Italian cities, the concept of foodification has emerged in recent years as a useful key-concept to analyse the outstanding relevance of food (both in terms of culinary offer and of discursive-imaginary constructions centred on it) within the context of wider processes of reconfiguration of the economic base of cities and of the entangling urban cultures. This contribution has thus a twofold objective: firstly, to reconstruct the conceptual genesis of foodification, also through connections with the international debates on the relationship between cities and food; and secondly, to illustrate how the articles collected in this special issue contribute to structuring and broadening the debate on foodification and its multiple urban implications.