
With the aim of developing knowledge production models that foster reciprocal learning between science and society, this article presents a theoretical and methodological proposal for applying the Quintuple Helix Model to the process of identifying and engaging both local and supra-local actors in citizen science projects. Specifically, it draws on the experience of the CS4RIVERS project, which focuses on monitoring, preserving, and restoring the biodiversity of the Ombrone River basin in the provinces of Siena and Grosseto (Italy). In this context, the Quintuple Helix Model is employed to map and analyse the network of involved actors, with the goal of reconstructing a relational system capable of generating place-based knowledge. This approach highlights the multiscalar, multi-level (in terms of the actors involved), and multi-sectoral (in terms of policy interventions) dimensions of the process, aimed at identifying territorial governance strategies that can effectively support sustainability transitions.