Sapienza University of Rome has developed an integrated model for educational innovation that combines faculty development with digital transformation through the Teaching and Learning Center and the Digital Education Hub ALMA. Designed to address the needs of a large and diverse academic community, the initiative promotes student-centered teaching by combining professional development, institutional coordination, and advanced digital technologies. AI-based tutors, remote laboratories, immersive learning environments, MOOCs, and collaborative platforms support innovative teaching practices while fostering accessibility, lifelong learning, and interdisciplinary collaboration. The experience demonstrates how coordinated governance and technological infrastructures can drive sustainable innovation and strengthen the quality of higher education.