The emergence of generative artificial intelligence (GenAI) is profoundly transforming the epistemological foundations of higher education. Universities are no longer faced solely with the challenge of integrating new technologies into teaching and learning processes; they are increasingly called upon to rethink the very nature of knowledge production, assessment, academic integrity and professional skills. This article argues that AI literacy should be understood as a new form of academic literacy, which goes beyond technical competence to encompass critical, ethical, epistemological and pedagogical dimensions. Drawing on recent international studies and emerging frameworks for AI literacy, the article discusses the implications of AI literacy for curriculum design, staff development and institutional transformation in higher education.