The article presents the first evidence on the adaptation and Italian validation of the Student Measure of Culturally Responsive Teaching scale aimed at measuring the perceptions of university students on culturally responsive teaching practices applied in classes. This instrument was administered to 336 students enrolled at the University of Siena. The data collected made it possible to conduct the exploratory factor analysis, confirming its trifactorial structure. The internal consistency of the Student Measure of Culturally Responsive Teaching and of the emerging factors was measured through the coefficient alpha whose results suggest that the Italian version of the instrument has a good internal consistency and a good level of reliability even with respect to its dimensions.