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Newsletter "Clinica dell'Alcolismo"

N. 46 (2016)

L’efficacia, la sicurezza e la maneggevolezza del sodio oxibato: i risultati dello studio GUM (GHB-Use and Misuse)

  • Ezio Manzato
  • Felice Nava
  • Gianmario Borroni
  • Elena Bosticco
  • Silvia Bravin
  • Giuseppe Fertonani Affini
  • Gianluigi Gasparini
  • Maura Richini
  • Mauro Thoux
  • Marta Torriani
  • Alfio Lucchini
Inviata
21 aprile 2017
Pubblicato
21-04-2017

Riferimenti bibliografici

  1. Addolorato G., Castelli E., Stefanini G.F., Casella G., Caputo F., Marsigli L., Bernardi M., Gasparini G. (1996), “An open multicentric study evaluating gamma-hydroxybutyric acid sodium salt in the mediumterm treatment of 179 alcohol dependent subjects”, Alcohol and Alcoholism, 31: 341-345.
  2. Addolorato G., Cibin M., Caputo F., Capristo E., Gessa G.L., Stefanini G.F., Gasbarrini G. (1998), “γ-Hydroxybutyric acid in the treatment of alcoholism: dosage fractioning utility in non-responder alcoholic patients”, Drug and Alcohol Dependence, 53: 7-10.
  3. Addolorato G., Balducci G., Capristo E., Attilia M.L., Taggi F., Gasbarrini G., Ceccanti M. (1999a), “Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepine”, Alcoholism: Clinical and Experimental Research, 23: 1596-1604.
  4. Addolorato G., Cibin N., Caputo F., Capristo E., Gessa G.L., Stefanini G.F., Gasbarrini G. (1999b), “Gamma-hydroxybutyric acid in the treatment of alcoholism: dosage fractioning utility in non-responder alcoholic patients”, Drug and Alcohol Dependence, 53: 7-10.
  5. Addolorato G., Caputo F., Capristo E., Stefanini G.F., Gasbarrini G. (2000), “Gamma-hydroxybutyric acid efficacy, potential abuse, and dependence in the treatment of alcohol addiction”, Alcoholism, 53: 7-10.
  6. Caputo F., Vignoli T., Maremmani I., Bernardi M., Zoli G. (2009a), “Gamma hydroxybutiric acid (GHB) for the treatment of alcohol dependence: A review”, International Journal of Environmental Research and Public Health, 6: 1917-1929.
  7. Caputo F., Francini S., Stoppo M., Lorenzini F., Vignoli T., Del Re A., Comaschi C., Leggio L., Addolorato G., Zoli G., Bernardi M. (2009b), “Incidence of craving for and abuse of gamma-hydroxybutyric acid (GHB) in different populations of treated alcoholics: an open comparative study”, Journal of Psychopharmacology, 23: 883-890.
  8. Caputo F., Francini S., Brambilla R., Vigna-Taglianti F., Stoppo M., Del Re A., Leggio L., Addolorato G., Zoli G., Bernardi M. (2011), “Sodium oxybate in maintaining alcohol abstinence in alcoholic patients with and without psychiatric comorbidity”, European Neuropsychopharmacology, 21: 450-456.
  9. Caputo F., Skala K., Walter H., Ceccanti M., Djurkowski M., Filipecka E., Florkowski A., Gerra G., Holzbach R., Horodnicki J., Platz W., Spazzapan B., Zblowska H., Bernardi M., Cacciaglia R., Vivet P., Lesch O.M., Addolorato G. (2013), “Sodium oxibate in the prevention of alcohol relapses in alcohol dependent patients (GATE 2 Study)”, Alcohol and Alcoholism, 48: S1-i33.
  10. Caputo F., Mirijello A., Cibin M., Mosti A., Ceccanti M., Domenicali M., Bernardi M., Maremmani I., Addolorato G., For the “Twentieth Anniversary of the Use of SMO in Italy” Group (2015), “Novel strategies to treat alcohol dependence with sodium oxybate according to clinical practice”, European Review for Medical and Pharmacological Sciences, 19: 1315-1320.
  11. Keating G.M. (2014), “Sodium oxybate: A review of its use in alcohol withdrawal syndrome and in the maintenance of abstinence in alcohol dependence”, Clinical Drug Investigation, 34: 63-80.
  12. Nava F., Premi S., Manzato E., Lucchini A. (2006), “Comparing treatment of alcoholism on craving and biochemical measures of alcohol consumption”, Journal of Psychoactive Drugs, 38: 211-217.
  13. Nava F., Premi S., Manzato E., Campagnola W., Lucchini A., Gessa G.L. (2007), “Gamma-hydroxybutyrate reduces both withdrawal syndrome and hypercortisolism in severe abstinent alcoholics: an open study vs. diazepam”, American Journal of Drug and Alcohol Abuse, 33: 379-392.
  14. Nava F., Vendramin A., Manzato E., Cibin M., Lucchini A. (2010), “New frontiers in alcoholism and addiction treatment”, Recent Patents on CNS Drug Discovery, 5: 81-94.
  15. Skala K., Caputo F., Mirijello A., Vassallo G. Antonelli M., Ferrulli A., Walter H., Lesch O.M., Addolorato G. (2014), “Sodium oxybate in the treatment of alcohol dependance: from the alcohol withdrawal syndrome to the alcohol relapse prevention”, Export Opinion on Pharmacotherapy, 15: 245-257.

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