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Saggi, Studi e Ricerche

N. 72 (2025)

Giovani e dipendenze da sostanza: vulnerabilità evolutiva e gravità clinica. Analisi descrittiva e psicopatologica di un campione di soggetti under 26 in trattamento presso la S.S.D. Nuove Dipendenze ONDA1 - Dipartimento Integrato Dipendenze - Asl città di Torino

DOI
https://doi.org/10.3280/mis72-2025oa21723
Inviata
17 dicembre 2025
Pubblicato
30-01-2026

Abstract

Over the last decades, age at onset of substance use has progressively decreased, with earlier initiation being associated with worse prognosis and greater clinical severity.
This descriptive study examined patterns of use, clinical severity and psychopathological dimensions in 111 patients under 26 years old treated at Onda1 - SSD Nuove Dipendenze Asl Città di Torino in 2024.
Assessments were based on clinical records, the Adolescent Behavior Questionnaire (ABQ) and the Seven Domains Addiction Scale (7DAS).
Cannabis was the most frequent primary substance (≈70%), but with increasing age a shift emerged towards crack, inhaled cocaine and polysubstance use, which reached 20% in the 23-25 age group. More than half of the sample (52.3%) presented severe Substance Use Disorder, with severity signifi cantly associated with age and substance pattern.
Although fewer in number, female patien ts showed more severe clinical impairment and higher levels of psychopathology across all 7DAS domains.
Overall, findings indicate an age-related trajectory of clinical worsening from adolescence to young adulthood and underline the need for specialized public services able to provide early, multidisciplinary and gender-sensitive interventions to intercept developmental vulnerability and prevent progression towards more complex and severe patterns of use.

Riferimenti bibliografici

  1. Balestra G., Rossi M., & Ferraro P. (2025). L’integrazione dei servizi di salute mentale e delle dipendenze: Rischi e prospettive. Rivista Italiana di Psichiatria, 60(1): 45-56.
  2. Bellavia A., Bellini A., D’Elia P., Gennari N., Ivaldi F., & Imperiale G. (2019). Come motivare al cambiamento giovani consumatori Animazione Sociale, 332: 63-94.
  3. Bifulco A., & Moran P. (2007). Clinical and research perspectives on child neglect and abuse: Implications for adult mental health.
  4. Psychiatry, 6(8): 339-342.
  5. Connor J.P., Gullo M.J., White A., & Kelly A.B. (2014). Polysubstance use: Diagnostic challenges, patterns of use and health. Drug and
  6. Alcohol Review, 33(3): 309-319.
  7. Eaton N.R., Keyes K.M., Krueger R.F., Noordhof A., Skodol A.E., Markon K.E., Grant B.F., & Hasin D.S. (2012). An invariant dimensional liability model of gender differences in mental disorder prevalence: Evidence from a national sample. Journal of Abnormal Psychology, 121(1): 282-288.
  8. Eaton N.R., Rodriguez-Seijas C., Carragher N., & Krueger R.F. (2018). Transdiagnostic factors of psychopathology and substance use disorders: A review. Social Psychiatry and Psychiatric Epidemiology, 53(5): 509-518.
  9. Gruppo Abele (2011). Quando un Ser.T. si mette in viaggio di conoscenza. Transizioni da una dimensione ambulatoriale ad una logica laboratoriale. Animazione Sociale, 78-89.
  10. Haro J.M., Altamura A.C., Correll C.U., Frydecka D., Nuijten M., & Patel A. (2023). Gender differences in clinical presentation and treatment outcomes in substance use disorders. Addiction, 118(6): 1151-1164.
  11. Hogrefe (2016). Adolescent Behavior Questionnaire (ABQ): Manuale di somministrazione e scoring. Hogrefe Editore.
  12. Meares R. (2005). The metaphor of play: Origin and breakdown of personal being. Routledge.
  13. Miller M.L., & Hurd Y.L. (2017). Testing the gateway hypothesis. Neuropsychopharmacology, 42(5): 985-986.
  14. Morgenstern J., & Leeds M. (1993). Individuals seeking treatment for substance use disorders: A clinical perspective on self-medication
  15. and affect regulation. Journal of Substance Abuse Treatment, 10(4): 285-296.
  16. Presidenza del Consiglio dei Ministri - Dipartimento Politiche Antidroga (2025). Relazione al Parlamento sul fenomeno delle tossicodipendenze.
  17. Publiedit (2004). L’onda lunga della cocaina. In: Dal fare al dire (Vol. III, dicembre 2004). Publiedit.
  18. Publiedit (2009). Il Progetto O.N.D.A.1. In: Interventi Innovativi per le Dipendenze Patologiche (Collana In-DIPENDENZE, gennaio 2009).
  19. Publiedit.
  20. Solmi M., Radua J., Olivola M., Croce E., Soardo L., Salazar de Pablo G., … & Fusar-Poli P. (2022). Age at onset of mental disorders worldwide: Large-scale meta-analysis of 192 epidemiological studies. Molecular Psychiatry, 27(1): 281-295.
  21. Starzer M.S.K., Nordentoft M., & Hjorthøj C. (2018). Rates and predictors of conversion to schizophrenia or bipolar disorder following substance-induced psychosis. American Journal of Psychiatry, 175(4): 343-350.
  22. Volkow N.D., Swanson J.M., Evins A.E., DeLisi L.E., Meier M.H., Gonzalez R., Bloomfi eld M.A.P., Curran H.V., Baler R., & Muenke M. (2014). Effects of cannabis use on human behavior, including cognition, motivation, and psychosis: A review. JAMA Psychiatry, 71(3): 292-297.
  23. Zerbini M. (2013). Costruzione, manutenzione ed implementazione di una effi cace rete territoriale: L’esperienza di O.N.D.A.1. Federserd
  24. Informa, 21: 7-8. Supplemento a Mission. Atti del Convegno “Costruire politiche sulle dipendenze”, Milano, giugno 2013.
  25. Zerbini M. (2014). Se la deve vedere lui… adolescenti, genitori, sostanze e servizi di cura. Federserd Informa, 25: 24-25. Supplemento a Mission. Atti del Convegno “Adolescenza, vulnerabilità, esordi psicotici, dipendenze”, Palermo, ottobre 2014.