This special issue aims to contribute to the debate on gender inequalities in academia and the gender equality policies that address them. In this introduction we offer an overview of the debate and of the main research issues and theoretical perspectives, showing how a multiplicity of approaches are needed for both understanding and transforming higher education institutions. Macro, meso and micro level approaches illuminate the gendered individual, cultural and institutional factors that constrain and enable academic life, with special attention paid to how the neoliberal turn, and its organizational consequences, exacerbates gender inequalities. Women, gender, care, and intersectionality approaches allow scholars to focus on the different gendered or intersectional relationships within academia. Policy-oriented approaches allow us to analyse and assess progress in institutional efforts to close the gap on gender inequalities in academia. Actor-centred studies expose the power struggles between actors that oppose or promote gender equality policies in academia.