This study aimed to explore the characteristics of the adaptation process for students with disabilities and identify factors influencing the effectiveness of their adaptation. The research was conducted at the Kyrgyz National University “J. Balasagyn” and the Kyrgyz State Technical University “I. Razzakov” from September 2023 to March 2024. The study involved 120 students with various forms of disabilities, studying in different courses and departments. The methodology included a comprehensive approach using psychodiagnostic methods, questionnaires, and structured interviews. Data analysis revealed that 68% of respondents experience difficulties in interacting with their peers. The universities involved in the study are ready to interact with students with disabilities; However, 72% of participants pointed out the insufficient accessibility of the educational environment, which complicates their social and academic adaptation. Additionally, 45% of respondents reported issues with self-esteem and confidence, which negatively affects their social activity and academic performance. A correlation was found between the level of socio-psychological adaptation and the availability of specialised support programmes at universities. Students who had access to psychological support and participated in social integration programmes demonstrated higher adaptation scores (30% higher) compared to those without such support. The research indicates that addressing the socio-psychological adaptation of this group of students requires a comprehensive approach aimed at improving their integration into the educational environment.